| The Chromosome 7 Annotation Project |
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| Gene / Transcript Structure |
| General information |
| Class | Known_Gene |
| TCAG Gene ID | GA0178 [Old ID: HSC7000178] |
| Gene Symbol | LEP [HUGO ID: LEP] |
| Gene Name | Leptin (obesity homolog, mouse) |
| Synonyms | OB, OBS |
| Summary | Summary: This gene is similar to the mouse obesity gene (ob). The protein encoded by this gene is secreted by white adipocytes. In the mouse study, mutations in this gene are linked to severe and morbid obesity. |
| Omim | Leptin (murine obesity homolog) | 164160 |
| Phenotype | Obesity, morbid, with hypogonadism [164160] Obesity, severe, due to leptin deficiency [164160] |
| Gene Ontology | ●Biological process Cell-cell signaling [GO:0007267] Energy reserve metabolism [GO:0006112] Signal transduction [GO:0007165] ●Cellular component Extracellular space [GO:0005615] ●Molecular function Hormone activity [GO:0005179] |
| Transcript | LEP | T00165 | U43653.1 |
| External links |
| Transcript Sequence(s) |
Note: Some data originated from NCBI's LocusLink.